William A Denny Selected Research

F1F0-ATP synthase

1/2021

Inhibitors of F1F0-ATP synthase enzymes for the treatment of tuberculosis and cancer.

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William A Denny Research Topics

Disease

72	Neoplasms (Cancer) 02/2022 - 01/2002
30	Hypoxia (Hypoxemia) 02/2022 - 01/2003
16	Tuberculosis (Tuberculoses) 01/2022 - 08/2008
6	Carcinoma (Carcinomatosis) 06/2013 - 01/2002
5	Visceral Leishmaniasis (Kala Azar) 02/2021 - 03/2016
5	Breast Neoplasms (Breast Cancer) 10/2020 - 12/2011
4	Glioblastoma (Glioblastoma Multiforme) 10/2021 - 02/2006
4	Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis) 01/2021 - 01/2019
4	Persistent Infection 09/2015 - 12/2010
3	Inflammation (Inflammations) 01/2022 - 11/2008
3	Neglected Diseases 01/2018 - 03/2016
3	Prostatic Neoplasms (Prostate Cancer) 01/2016 - 09/2012
3	Ovarian Neoplasms (Ovarian Cancer) 01/2016 - 10/2012
3	Infections 09/2015 - 08/2013
3	Leukemia 02/2014 - 02/2012
2	Brain Neoplasms (Brain Tumor) 10/2021 - 01/2021
2	Adenocarcinoma 01/2018 - 02/2016
2	Graft vs Host Disease (Graft-Versus-Host Disease) 09/2017 - 01/2017
2	Genomic Instability 01/2015 - 02/2011
2	Lymphoma (Lymphomas) 02/2012 - 12/2008
2	Renal Cell Carcinoma (Grawitz Tumor) 01/2010 - 07/2008
2	Poisoning 01/2003 - 02/2002
2	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 01/2002 - 01/2002
1	Glomerulonephritis 11/2021
1	Chronic Kidney Failure (Chronic Renal Failure) 11/2021
1	Giant Cell Tumors (Giant Cell Tumor) 02/2021
1	Chagas Disease (American Trypanosomiasis) 12/2020

Drug/Important Bio-Agent (IBA)

42	Pharmaceutical PreparationsIBA 01/2022 - 02/2002
25	ProdrugsIBA 02/2022 - 03/2002
15	EnzymesIBA 02/2022 - 01/2002
15	DNA (Deoxyribonucleic Acid)IBA 03/2012 - 03/2002
13	Tirapazamine (SR 4233)IBA 10/2010 - 01/2003
12	Alkylating AgentsIBA 07/2013 - 03/2002
10	Cytotoxins (Cytolysins)IBA 03/2010 - 01/2002
7	bedaquiline (R207910)IBA 01/2021 - 10/2017
7	Proteins (Proteins, Gene)FDA Link 01/2019 - 01/2002
6	pretomanidIBA 12/2020 - 01/2010
5	Protein Isoforms (Isoforms)IBA 01/2020 - 05/2012
5	OPC-67683IBA 01/2017 - 12/2010
4	Phosphotransferases (Kinase)IBA 11/2021 - 08/2006
4	Coloring Agents (Dyes)IBA 10/2021 - 01/2019
4	pyridineIBA 01/2021 - 12/2010
4	Adenosine Triphosphate (ATP)IBA 01/2021 - 08/2011
4	PerforinIBA 09/2017 - 12/2008
4	Aldo-Keto ReductasesIBA 02/2014 - 03/2010
4	LigandsIBA 07/2013 - 09/2004
4	cyclenIBA 07/2013 - 09/2004
4	DuocarmycinsIBA 03/2012 - 03/2011
4	Mechlorethamine (Nitrogen Mustard)FDA Link 03/2010 - 04/2003
3	Temozolomide (Temodar)FDA LinkGeneric 10/2021 - 01/2019
3	OxazinesIBA 02/2021 - 01/2017
3	Antitubercular AgentsIBA 01/2017 - 12/2010
3	quinolineIBA 03/2016 - 11/2008
3	Anti-Bacterial Agents (Antibiotics)IBA 01/2016 - 10/2011
3	Oxygen (Dioxygen)IBA 07/2013 - 11/2008
3	Phosphates (Orthophosphate)IBA 03/2012 - 03/2011
3	tretazicarIBA 06/2004 - 03/2002
2	heptamethine cyanine dyeIBA 10/2021 - 01/2019
2	CarbamatesIBA 02/2021 - 01/2012
2	NitroimidazolesIBA 12/2020 - 01/2018
2	Oxidoreductases (Dehydrogenase)IBA 10/2020 - 01/2006
2	Peptides (Polypeptides)IBA 01/2020 - 01/2017
2	Biological ProductsIBA 04/2019 - 08/2010
2	AmidesIBA 04/2019 - 01/2012
2	Cytostatic AgentsIBA 01/2019 - 12/2011
2	DiarylquinolinesIBA 01/2019 - 10/2017
2	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 07/2017 - 10/2012
2	persinIBA 01/2016 - 12/2011
2	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 01/2016 - 01/2002
2	PoisonsIBA 01/2016 - 05/2004
2	Estrogen ReceptorsIBA 01/2016 - 01/2014
2	TriazinesIBA 06/2014 - 11/2008
2	CEN-209IBA 06/2014 - 10/2010
2	Hormones (Hormone)IBA 02/2014 - 01/2014
2	CobaltIBA 07/2013 - 08/2011
2	AcidsIBA 09/2012 - 01/2010
2	BromidesIBA 03/2012 - 10/2011
2	Antineoplastic Agents (Antineoplastics)IBA 02/2012 - 06/2004
2	3-amino-1,2,4-benzotriazineIBA 03/2010 - 06/2005
2	PR-104AIBA 03/2010 - 07/2007
2	PR-104IBA 03/2010 - 07/2007
2	NitrogenIBA 01/2009 - 11/2008
2	Gemcitabine FDA Link 01/2009 - 07/2007
2	Type II DNA Topoisomerases (Topoisomerase II)IBA 02/2007 - 02/2002
2	Free RadicalsIBA 06/2005 - 11/2003
2	trioctyl phosphine oxide (TOPO)IBA 05/2004 - 01/2003
2	Type I DNA Topoisomerases (Topoisomerase I)IBA 01/2003 - 01/2002
1	MitogensIBA 01/2022
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2022
1	Discoidin Domain ReceptorsIBA 11/2021
1	troxipideIBA 10/2021
1	Investigational DrugsIBA 02/2021
1	pexidartinibIBA 02/2021
1	Mitochondrial Proton-Translocating ATPases (Mitochondrial ATP Synthase)IBA 01/2021
1	F1F0-ATP synthaseIBA 01/2021
1	Drug CarriersIBA 01/2021

Therapy/Procedure

24	Therapeutics 02/2022 - 03/2002
9	Drug Therapy (Chemotherapy) 02/2022 - 01/2002
5	Radiotherapy 02/2022 - 01/2004
2	Aftercare (After-Treatment) 07/2007 - 08/2006